Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415618 | 0.83 | PDE4B (0.43) | ALDH1A1MAPK1BACE1NPC1PLA2G1B | |
| SCHEMBL9293119 | 0.77 | AKR1C3 (0.36) | NPC1RAB9A | |
| SCHEMBL13376117 | 0.77 | EGFR (0.38) | ALDH1A1MAPK1PDE4APDE4BPDE4C | |
| SCHEMBL13508914 | 0.77 | THRB (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13044012 | 0.76 | THRA (0.42) | MAPK1RXRARXRBRXRG | |
| SCHEMBL9293194 | 0.75 | KIF11 (0.40) | ALDH1A1MAPK1NPC1PLA2G1BNFKB1 | |
| SCHEMBL13773460 | 0.74 | PDE4B (0.49) | ALDH1A1BACE1NPC1PLA2G1BNFKB1 | |
| SCHEMBL3418407 | 0.73 | CRHBP (0.48) | ALDH1A1MAPK1BACE1NPC1PLA2G1B | |
| SCHEMBL25976215 | 0.73 | NPC1 (0.38) | ALDH1A1MAPK1BACE1NPC1PLA2G1B | |
| Potassium Ion SCHEMBL3416456 | 0.72 | ALDH1A1 (0.38) | ALDH1A1MAPK1BACE1NPC1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350846-A | Antibiotics | MERCK & CO., INC. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5208329-A | Antibacterial agents | MERCK & CO., INC. (US) | 1993-05-04 | — | — | US | disclosed |
| US-5182385-A | Chemical intermediates for bactericides | MERCK & CO., INC. (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0467434-A1 | 2-Biphenyl-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0464900-A2 | 2-Biphenyl-carbapenems | MERCK & CO. INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| US-5025006-A | Carbapenicillin antibiotics | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |
| US-5011832-A | 2-biphenyl-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-04-30 | — | — | US | disclosed |