Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947532 | 0.83 | CASP6 (0.43) | PSIP1KDM4ESMN1; SMN2CA1CA2 | |
| Hydrochloric Acid SCHEMBL28000098 | 0.82 | PSIP1 (0.47) | PSIP1KDM4ESMN1; SMN2HTR6CA1 | |
| SCHEMBL7564333 | 0.77 | RAPGEF4 (0.51) | KDM4EHTR6POLBRECQLMAPT | |
| SCHEMBL1804054 | 0.77 | ESR2 (0.40) | PSIP1KDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL8981201 | 0.75 | CASP6 (0.43) | KDM4ESMN1; SMN2HTR6CA1CA2 | |
| SCHEMBL29074448 | 0.75 | ALDH1A1 (0.47) | KDM4EHTR6CA1CA2CA12 | |
| SCHEMBL8030396 | 0.75 | CA2 (0.39) | PSIP1KDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL27264469 | 0.75 | AOC1 (0.35) | KDM4EHTR6CA1CA2POLB | |
| SCHEMBL8947534 | 0.74 | CA2 (0.44) | PSIP1KDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL14043172 | 0.74 | HRH3 (0.39) | LOXL2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359043-A | Reactive dyes having a sulphonamido group | ZENECA LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |
| EP-0514001-A1 | Reactive dyes | ZENECA LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |
| US-4748236-A | Azo dyestuffs having sulpho ortho to azo bridge and containing two triazine reactive groups | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |