Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847718 | 0.90 | CYP11B2 (0.35) | RORCJAK2JAK1TYK2JAK3 | |
| SCHEMBL9301575 | 0.86 | RORC (0.39) | RORC | |
| SCHEMBL9302442 | 0.79 | RORC (0.41) | RORC | |
| SCHEMBL9301682 | 0.74 | RORC (0.42) | RORC | |
| SCHEMBL9303809 | 0.74 | HTT (0.41) | RORC | |
| SCHEMBL9847732 | 0.73 | HTT (0.43) | RORC | |
| SCHEMBL9301471 | 0.72 | RORC (0.41) | RORC | |
| SCHEMBL9302252 | 0.72 | ACHE (0.42) | RORC | |
| SCHEMBL9301681 | 0.71 | HTT (0.42) | RORC | |
| SCHEMBL9301969 | 0.70 | GRM5 (0.42) | RORCTOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |