Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847719 | 0.87 | DRD3 (0.47) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9303256 | 0.86 | GAA (0.45) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9301930 | 0.86 | HTT (0.45) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9303370 | 0.78 | ALDH1A1 (0.43) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9301127 | 0.78 | DRD3 (0.39) | ALDH1A1KDM4EMEN1KMT2ADRD3 | |
| SCHEMBL25780379 | 0.76 | HSD17B10 (0.49) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9847735 | 0.76 | HTT (0.43) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9302880 | 0.75 | HTT (0.46) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9301581 | 0.74 | HTT (0.50) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9302147 | 0.73 | GAA (0.41) | HTTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |