Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301969 | 0.92 | GRM5 (0.42) | GRM5ALDH1A1HPGDOPRM1OPRD1 | |
| SCHEMBL9302252 | 0.89 | ACHE (0.42) | GRM5OPRM1OPRD1OGFRL1LMNA | |
| SCHEMBL9303370 | 0.87 | ALDH1A1 (0.43) | GRM5ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL9303690 | 0.83 | OPRM1 (0.37) | OPRM1OPRD1OPRK1OGFRL1CPT1A | |
| SCHEMBL9302311 | 0.81 | CYP11B2 (0.44) | ALDH1A1KDM4EHPGDNPC1CSF1R | |
| Hydrochloric Acid SCHEMBL9302957 | 0.81 | CYP11B1 (0.43) | ALDH1A1KDM4EHPGDNPC1CSF1R | |
| SCHEMBL9301930 | 0.79 | HTT (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| Acetic Acid SCHEMBL9301936 | 0.78 | CYP11B2 (0.44) | ALDH1A1KDM4EHPGDNPC1MEN1 | |
| SCHEMBL9301682 | 0.75 | RORC (0.42) | OPRM1OPRD1OGFRL1SMN1; SMN2LMNA | |
| SCHEMBL9303809 | 0.74 | HTT (0.41) | ALDH1A1OPRM1OPRD1OGFRL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |