Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302354 | 0.91 | EPHX2 (0.45) | ALDH1A1KMT2AEPHX2L3MBTL1MEN1 | |
| SCHEMBL9302183 | 0.90 | CYP2D6 (0.44) | ALDH1A1KMT2AL3MBTL1MEN1POLB | |
| SCHEMBL9301890 | 0.88 | L3MBTL1 (0.46) | ACHEALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL9301405 | 0.82 | ACHE (0.46) | ACHEALDH1A1EPHX1KMT2ASMN1; SMN2 | |
| SCHEMBL9301293 | 0.76 | LMNA (0.46) | ALDH1A1KMT2ASMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL9302070 | 0.73 | EPHX2 (0.47) | ALDH1A1KMT2AKDM4EEPHX2L3MBTL1 | |
| SCHEMBL9302303 | 0.73 | EPHX2 (0.47) | ALDH1A1KMT2ASMN1; SMN2KDM4EEPHX2 | |
| SCHEMBL9301424 | 0.73 | ADRA1A (0.45) | ACHEEPHX1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL9301986 | 0.73 | CYP2D6 (0.46) | ALDH1A1KMT2AL3MBTL1MEN1POLB | |
| SCHEMBL9302730 | 0.71 | EPHX2 (0.51) | ALDH1A1KMT2AKDM4EEPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |