Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302354 | 0.90 | EPHX2 (0.45) | MGLLMEN1KMT2AHSD11B1UBE2M | |
| SCHEMBL9301418 | 0.90 | ACHE (0.43) | CYP2C19MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9301890 | 0.88 | L3MBTL1 (0.46) | MGLLHSD11B1UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL9301986 | 0.84 | CYP2D6 (0.46) | CYP2D6CYP2C19MGLLMEN1KMT2A | |
| SCHEMBL9302190 | 0.77 | MGLL (0.45) | CYP2D6CYP2C19MGLLMEN1KMT2A | |
| SCHEMBL9302070 | 0.74 | EPHX2 (0.47) | MGLLMEN1KMT2AHSD11B1UBE2M | |
| SCHEMBL9302303 | 0.74 | EPHX2 (0.47) | MGLLMEN1KMT2AHSD11B1UBE2M | |
| SCHEMBL9301807 | 0.73 | TSHR (0.45) | MEN1KMT2AHSD11B1UBE2MDCUN1D1 | |
| SCHEMBL9301405 | 0.73 | ACHE (0.46) | CYP2C19KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL9302730 | 0.72 | EPHX2 (0.51) | MGLLMEN1KMT2AHSD11B1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |