Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304172 | 0.97 | KDM4E (0.34) | CASP3CASP7MEN1KMT2AMAOB | |
| SCHEMBL9809787 | 0.93 | MEN1 (0.35) | MEN1KMT2AMAOBCYP3A4KDM4E | |
| SCHEMBL9809777 | 0.84 | MAOB (0.40) | KMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL9302379 | 0.80 | MAOB (0.36) | CASP3CASP7MEN1KMT2AMAOB | |
| SCHEMBL9304354 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1DRD4 | |
| SCHEMBL9304584 | 0.76 | MAOB (0.37) | MAOBKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL9303640 | 0.74 | KMT2A (0.36) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9302635 | 0.73 | MAOB (0.36) | MAOBUSP2ALDH1A1LMNA | |
| SCHEMBL8980658 | 0.72 | PKM (0.37) | MAOBALDH1A1TSHR | |
| SCHEMBL8367091 | 0.71 | ALDH1A1 (0.39) | CASP7MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071850-A | Cardiovascular disorders | PIERRE FABRE MEDICAMENT (FR) | 1991-12-10 | — | — | US | disclosed |