Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040962 | 0.91 | ABCB11 (0.45) | ABCB11CES2ADRA1APIK3CDPIK3CA | |
| SCHEMBL23841300 | 0.85 | CES2 (0.47) | ABCB11CES2ADRA1AALOX5APFEN1 | |
| SCHEMBL28230701 | 0.84 | ALOX5AP (0.46) | ABCB11ADRA1AALOX5APFEN1KIF11 | |
| SCHEMBL168415 | 0.82 | L3MBTL1 (0.55) | ABCB11ADRA1AALOX5APFEN1KIF11 | |
| SCHEMBL795545 | 0.81 | CES2 (0.52) | ABCB11CES2TRPV4MCL1 | |
| SCHEMBL5831189 | 0.81 | KIF11 (0.44) | ABCB11PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14684308 | 0.81 | ADRA1A (0.43) | ABCB11ADRA1AALOX5APFEN1KIF11 | |
| SCHEMBL12879058 | 0.81 | PIK3CD (0.44) | ABCB11PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29374110 | 0.81 | TRPV4 (0.60) | ABCB11CES2TRPV4MCL1 | |
| SCHEMBL3611597 | 0.81 | TRPV4 (0.60) | ABCB11CES2TRPV4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369116-A | Polyfluorinated thiazoline derivative and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-11-29 | — | — | US | disclosed |