Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.45 |
| ▸ | ITGAL | P20701 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477507 | 0.84 | TACR1 (0.46) | L3MBTL1THRBLMNAALDH1A1TACR1 | |
| SCHEMBL38327 | 0.83 | L3MBTL1 (0.49) | L3MBTL1ITGB1ITGA4MAPTPTGS2 | |
| Afalanine SCHEMBL9603419 | 0.83 | L3MBTL1 (0.69) | L3MBTL1ITGB1ITGA4LMNAGNPAT | |
| SCHEMBL18655444 | 0.82 | LMNA (0.45) | L3MBTL1ITGB1ITGA4KDM4EMAPT | |
| SCHEMBL8815317 | 0.82 | L3MBTL1 (0.52) | L3MBTL1ITGB1ITGA4KDM4EMAPT | |
| SCHEMBL10477404 | 0.79 | ACE (0.56) | L3MBTL1ITGB1ITGB3ITGA2BCTSS | |
| SCHEMBL18659591 | 0.78 | ALOX15 (0.43) | L3MBTL1ITGB1ITGA4KDM4EMAPT | |
| Acetylleucine SCHEMBL9595190 | 0.78 | ALDH1A1 (0.69) | LMNAALDH1A1 | |
| SCHEMBL9595472 | 0.78 | L3MBTL1 (0.44) | L3MBTL1ITGB1ITGA4KDM4EMAPT | |
| Afalanine SCHEMBL331330 | 0.77 | CTSS (0.65) | L3MBTL1LMNAGNPATCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364850-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5272175-A | Substituted tyrosyl diamide compounds | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |