Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.34 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.34 |
| ▸ | VKORC1 known ✓ | Q9BQB6 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL931197 | 0.97 | TYR (0.43) | TYRPKLRKDM4EALDH1A1HPGD | |
| SCHEMBL9771270 | 0.97 | TYR (0.43) | TYRPKLRKDM4EALDH1A1HPGD | |
| SCHEMBL11759865 | 0.97 | TYR (0.43) | TYRPKLRKDM4EALDH1A1HPGD | |
| SCHEMBL312340 | 0.86 | TYR (0.46) | TYRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9771279 | 0.85 | TYR (0.45) | TYRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL11759875 | 0.85 | TYR (0.45) | TYRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL11759869 | 0.85 | TYR (0.45) | TYRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL931199 | 0.85 | TYR (0.45) | TYRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8425731 | 0.85 | TYR (0.45) | TYRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8571097 | 0.85 | TYR (0.45) | TYRKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328884-A | Salicylic acid salt,and amide or sulfonamide as developer | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5250108-A | Mixture of salicylic acid salt, amide and sulfonamide compounds | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0322091-B1 | PROCESS FOR PREPARING ZINC SALT OF SALICYCLIC ACID COMPOUND | Fuji Photo Film Co., Ltd. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-4914219-A | Process for preparing zinc salt of salicylic acid compound | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0322091-A2 | Process for preparing zinc salt of salicyclic acid compound | Fuji Photo Film Co., Ltd. (JP) | 1989-06-28 | — | — | EP | disclosed |
| US-4134847-A | HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1979-01-16 | — | — | US | disclosed |