Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310909 | 0.85 | NPC1 (0.32) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9308311 | 0.85 | KDM4E (0.44) | POLBKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7312950 | 0.78 | KDM4E (0.53) | POLBKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9309273 | 0.74 | AGTR1 (0.34) | — | |
| SCHEMBL9310915 | 0.71 | AGTR1 (0.33) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7302856 | 0.70 | AR (0.38) | POLBKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21810462 | 0.69 | TAS2R14 (0.46) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL7302158 | 0.68 | SLC6A3 (0.46) | POLBKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9309854 | 0.66 | TSHR (0.47) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9139315 | 0.65 | CSNK2A1 (0.53) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |