Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374128 | 0.87 | LMNA (0.58) | GAAROCK2CCR2ROCK1LTA4H | |
| SCHEMBL7294948 | 0.85 | PRKAB2 (0.56) | PKMLTA4HACHECYP3A4CYP2C9 | |
| SCHEMBL9412142 | 0.79 | DRD4 (0.61) | PKMDRD4DRD2DRD3GAA | |
| SCHEMBL7364603 | 0.79 | CA12 (0.58) | PKMDRD4DRD2DRD3LMNA | |
| SCHEMBL11060430 | 0.78 | NR3C1 (0.58) | PKMDRD2GAAKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11042554 | 0.77 | NR3C1 (0.57) | PKMDRD2GAAKMT2ALMNA | |
| SCHEMBL15586883 | 0.76 | PKM (0.47) | PKMDRD4DRD2DRD3GAA | |
| SCHEMBL7289534 | 0.76 | KMT2A (0.70) | ROCK2CCR2ROCK1LTA4HKMT2A | |
| SCHEMBL1716567 | 0.74 | ROCK2 (0.79) | ROCK2CCR2ROCK1 | |
| SCHEMBL15545214 | 0.73 | ACHE (0.49) | PKMDRD4DRD2DRD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306719-A | Cardiotonic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |