SCHEMBL9319787

SCHEMBL9319787

CCOC(=O)C(c1ccc(C)cc1)N(C)C(=O)Cc1c(Cl)cccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
NPC1 O15118 1/20 0.39
HTT P42858 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 2/20 0.37
UTS2R Q9UKP6 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CNR2 P34972 1/20 0.36
NLRP3 Q96P20 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321052 0.94 UTS2R (0.42) AKR1B1KMT2AMEN1NPC1HTT
SCHEMBL9319501 0.91 AKR1B1 (0.44) AKR1B1KMT2AMEN1NPC1HTT
SCHEMBL9318865 0.89 SMN1; SMN2 (0.42) KMT2AMEN1NPC1ALDH1A1UTS2R
SCHEMBL9318635 0.86 ALDH1A1 (0.39) AKR1B1KMT2AMEN1NPC1HTT
SCHEMBL9319221 0.83 CASP1 (0.47) AKR1B1KMT2AMEN1NPC1HTT
SCHEMBL8744771 0.82 RORC (0.46) AKR1B1KMT2AMEN1NPC1HTT
SCHEMBL9321113 0.82 SMN1; SMN2 (0.38) KMT2AMEN1UTS2RCYP1A2CYP2C9
SCHEMBL9319873 0.81 CYP3A4 (0.45) KMT2AHTTSIGMAR1ALDH1A1KDM4E
SCHEMBL9318567 0.81 KMT2A (0.39) AKR1B1KMT2AMEN1NPC1HTT
SCHEMBL9320932 0.80 OPRM1 (0.47) ALDH1A1UTS2RCYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5350861-A Insecticides, acaricides, fungicides, antimycotic agents BAYER AKTIENGESELLSCHAFT (DE) 1994-09-27 US disclosed