Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | ELOC | Q15369 | 1/20 | 0.35 |
| ▸ | ELOB | Q15370 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862219 | 0.85 | ACMSD (0.47) | PTGS2TSHRMKNK1MKNK2HDAC2 | |
| SCHEMBL7801462 | 0.76 | LSS (0.33) | — | |
| SCHEMBL9090385 | 0.76 | CA1 (0.35) | CA1CA2 | |
| SCHEMBL11310791 | 0.76 | MKNK1 (0.56) | PTGS2TSHRMKNK1MKNK2PRSS1 | |
| SCHEMBL679970 | 0.76 | MKNK1 (0.56) | PTGS2TSHRMKNK1MKNK2PRSS1 | |
| SCHEMBL9811873 | 0.74 | LMNA (0.59) | TSHRCA2PTGS1 | |
| SCHEMBL14067029 | 0.73 | MAPK1 (0.46) | — | |
| SCHEMBL2424766 | 0.73 | PTGS2 (0.33) | PTGS2TSHRMKNK1MKNK2PDCD1 | |
| SCHEMBL9120467 | 0.73 | CALM1 (0.52) | LTA4HCA12CA1CA2CA9 | |
| SCHEMBL10760848 | 0.73 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986848-A | Pultruded polyurethane door and window composite material and preparation method thereof | 河北聚久复合材料有限公司 | 2024-05-07 | — | — | CN | claimed |
| US-5349095-A | Process for preparing hydroxyalkylbenzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1994-09-20 | — | — | US | claimed |
| US-5264613-A | Process for preparing ester of hydroxymethylbenzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | claimed |
| CN-117986848-A | Pultruded polyurethane door and window composite material and preparation method thereof | 河北聚久复合材料有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117986848-A | Pultruded polyurethane door and window composite material and preparation method thereof | 河北聚久复合材料有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-5349095-A | Process for preparing hydroxyalkylbenzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1994-09-20 | — | — | US | disclosed |
| US-5264613-A | Process for preparing ester of hydroxymethylbenzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5264613-A | Process for preparing ester of hydroxymethylbenzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0251357-B1 | ENGINEERING THERMOPLASTICS CONTAINING PENDANT BENZOCYCLOBUTENE GROUPS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-07-17 | — | — | EP | disclosed |
| EP-0251357-A1 | Engineering thermoplastics containing pendant benzocyclobutene groups | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-01-07 | — | — | EP | disclosed |
| US-4708994-A | CURING, CROSSLINKING; SOLVENT RESISTANCE | SHELL OIL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |