SCHEMBL7801462

SCHEMBL7801462

ICc1ccc(C2=CCC2)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LSS P48449 1/20 0.33
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18724371 0.85 ACMSD (0.44) LSSHRH3
SCHEMBL9320716 0.76 PTGS2 (0.41)
SCHEMBL679947 0.76 HRH3 (0.47) HRH3
SCHEMBL10760848 0.73 SIGMAR1 (0.33) LSSHRH3
SCHEMBL9120467 0.73 CALM1 (0.52)
SCHEMBL649682 0.72 ALDH1A1 (0.37) HRH3
SCHEMBL9347469 0.72 CXCR3 (0.34)
SCHEMBL9092592 0.71 ALDH1A1 (0.44)
SCHEMBL9811873 0.70 LMNA (0.59)
SCHEMBL9093115 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599886-B1 MACROMONOMERS HAVING REACTIVE END GROUPS MISSISSIPPI POLYMER TECH INC (US) 2001-03-21 EP disclosed
US-5973075-A POLYPHENYL RESINS MAXDEM INCORPORATION (US) 1999-10-26 US disclosed
US-5827927-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1998-10-27 US disclosed
US-5824744-A RIGID POLYMER RODS AND MACROMONOMERS WITH REACTIVE END GROUPS FOR REINFORCEMENT MAXDEM INCORPORATED (US) 1998-10-20 US disclosed
US-5670564-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1997-09-23 US disclosed
EP-0599886-A4 MACROMONOMERS HAVING REACTIVE END GROUPS. MAXDEM INC (US) 1996-07-24 EP disclosed
EP-0599886-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1994-06-08 EP disclosed
WO-1993004099-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed