Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322225 | 0.95 | THRA (0.40) | GAASMN1; SMN2TP53THRATHRB | |
| SCHEMBL9324758 | 0.94 | LTA4H (0.42) | GAASMN1; SMN2TP53THRATHRB | |
| SCHEMBL9321412 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2TP53HSD17B10ALDH1A1GNAI3 | |
| SCHEMBL9323677 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53HSD17B10GNAI3GNAO1 | |
| SCHEMBL9322356 | 0.82 | BCHE (0.47) | SMN1; SMN2TP53HSD17B10ALDH1A1GNAI3 | |
| SCHEMBL24633509 | 0.82 | TP53 (0.47) | GAASMN1; SMN2TP53THRATHRB | |
| SCHEMBL9323550 | 0.81 | TP53 (0.39) | SMN1; SMN2TP53FPR3FPR2 | |
| SCHEMBL9323743 | 0.78 | THRA (0.40) | GAASMN1; SMN2TP53THRATHRB | |
| SCHEMBL9323712 | 0.77 | SMN1; SMN2 (0.50) | GAASMN1; SMN2HSD17B10ALDH1A1GNAI3 | |
| SCHEMBL9322261 | 0.77 | HRH3 (0.36) | SMN1; SMN2TP53FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |