Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324433 | 0.79 | SIGMAR1 (0.39) | TAAR1DRD2DRD3OPRM1OPRK1 | |
| SCHEMBL9325409 | 0.78 | TDP1 (0.40) | DRD2DRD3OPRK1 | |
| SCHEMBL9326394 | 0.77 | LTA4H (0.41) | DRD2DRD3OPRK1 | |
| SCHEMBL9325760 | 0.74 | CA12 (0.46) | — | |
| SCHEMBL9327603 | 0.74 | LMNA (0.53) | OPRM1OPRK1OPRD1 | |
| SCHEMBL9327633 | 0.72 | KCNH2 (0.50) | — | |
| SCHEMBL9326379 | 0.71 | KCNH2 (0.50) | PTGS2 | |
| SCHEMBL9324382 | 0.70 | KDM4E (0.39) | DRD3 | |
| SCHEMBL9325455 | 0.70 | HTR2A (0.39) | TAAR1DRD2DRD3 | |
| SCHEMBL4135682 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |