Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93119 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL7265188 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL7259740 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL2111100 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL10383717 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL2108217 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL7264534 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL7264535 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL2112303 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT | |
| SCHEMBL2110530 | 0.98 | FAAH (0.43) | OPRM1FAAHCNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | claimed |
| CN-115850328-A | Diphosphine ligand with cyclopropane skeleton and cobalt complex thereof, preparation method and application | 南开大学 | 2023-03-28 | — | — | CN | claimed |
| US-20220162219-A1 | Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof | UNIV JINAN (CN) | 2022-05-26 | — | — | US | claimed |
| CN-114249725-A | Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof | 南开大学 | 2022-03-29 | — | — | CN | claimed |
| CN-114014878-A | Novel conjugated alkenyl zinc reagent, preparation method and application thereof | 南开大学 | 2022-02-08 | — | — | CN | claimed |
| CN-114014879-A | Optically active biaryl borane adduct and preparation method and application thereof | 南开大学 | 2022-02-08 | — | — | CN | claimed |
| CN-106518931-B | Novel iridium complex of spiro phosphine-carboxylic acid and preparation method and application thereof | 南开大学 | 2021-08-24 | — | — | CN | claimed |
| CN-112209967-A | Chiral spiro monophosphine-oxazoline ligand and preparation method thereof | 瑞博(杭州)医药科技有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-111909206-A | Chiral spiro monophosphine ligand and preparation method thereof | 浙江瑞博制药有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111393466-A | Gem disilicon compound, preparation method and application thereof | 南开大学 | 2020-07-10 | — | — | CN | claimed |
| US-20140194638-A1 | Spirobenzylamine-Phosphine, Preparation Method Therefor And Use Thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2014-07-10 | — | — | US | claimed |
| EP-2752419-A1 | SPIROBENZYLAMINE-PHOSPHINE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2014-07-09 | — | — | EP | claimed |
| US-8450493-B2 | Spiro phosphine-oxazoline, preparation method and application thereof | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2013-05-28 | — | — | US | claimed |
| US-20110118472-A1 | Spiro Phosphine-Oxazoline, Preparation Method and Application thereof | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-05-19 | — | — | US | claimed |
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-04-21 | — | — | US | claimed |
| EP-2275398-A1 | APPLICATION OF THE IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION FOR UNSATURATED CARBOXYLIC ACID | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-01-19 | — | — | EP | claimed |
| EP-2272853-A1 | SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-01-12 | — | — | EP | claimed |
| EP-0599906-B1 | HERBICIDES CONTAINING 3-AMINOBENZO B]THIOPHENES AS AN ANTIDOTE | BASF AG (DE) | 1997-01-15 | — | — | EP | claimed |
| EP-0599906-A1 | HERBICIDES CONTAINING 3-AMINOBENZO B]THIOPHENES AS AN ANTIDOTE. | BASF AG (DE) | 1994-06-08 | — | — | EP | claimed |
| WO-1993004057-A2 | HERBICIDES CONTAINING 3-AMINOBENZO[B]THIOPHENES AS AN ANTIDOTE | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | HDHD5, ELOVL5, FASN | OPRM1 654/4885FAAH 334/4885CNR1 1786/4885 |
| US-20220162219-A1 | Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof | FHIT, BCAT1, BCAT2 | OPRM1 374/4885FAAH 147/4885CNR1 782/4885 |
| US-20140194638-A1 | Spirobenzylamine-Phosphine, Preparation Method Therefor And Use Thereof | FAR1, WEE1, ALDH7A1 | OPRM1 2476/4885FAAH 989/4885CNR1 2427/4885 |
| US-20110118472-A1 | Spiro Phosphine-Oxazoline, Preparation Method and Application thereof | ADH1A, ADH1C, ALDH7A1 | OPRM1 1014/4885FAAH 4221/4885CNR1 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.