SCHEMBL9964995

SCHEMBL9964995

C=Cc1ccccc1/C=N\C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CASP1 P29466 1/20 0.36
TSHR P16473 4/20 0.35
MAPK1 P28482 2/20 0.33
FGF23 Q9GZV9 1/20 0.32
MAOB P27338 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL29266735 0.79 ALDH1A1 (0.57) ALDH1A1LMNATSHRHDAC8MEN1
SCHEMBL29405187 0.79 ALDH1A1 (0.63) ALDH1A1LMNATSHRHSD17B10HDAC8
SCHEMBL473080 0.79 ALDH1A1 (0.63) ALDH1A1LMNATSHRHSD17B10HDAC8
SCHEMBL7638 0.79 ALDH1A1 (0.63) ALDH1A1LMNATSHRHSD17B10HDAC8
Methyl Alcohol SCHEMBL28639807 0.76 ALDH1A1 (0.55) ALDH1A1MAPTLMNATSHRMAPK1
Propene SCHEMBL7948571 0.76 ALDH1A1 (0.55) ALDH1A1LMNATSHRHDAC8MEN1
SCHEMBL14229986 0.76 ALDH1A1 (0.44) ALDH1A1LMNATSHRMAPK1MAOB
SCHEMBL26622733 0.76 ALDH1A1 (0.44) ALDH1A1LMNAKDM4ETSHRMAPK1
SCHEMBL15133699 0.76 RAB9A (0.38) ALDH1A1RAB9ASMN1; SMN2GAAMAPT
SCHEMBL9328343 0.76 HPGD (0.52) ALDH1A1RAB9AMAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12038650-B2 Multilayer phase difference plate, polarizing plate, and image display device ZEON CORPORATION (JP) 2024-07-16 US disclosed
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-17 US disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 US disclosed
US-11647668-B2 Organometallic compound and organic light-emitting device including the same Samsung Display Co., Lid. (KR) 2023-05-09 US disclosed
US-20230016922-A1 VISIBLE-LIGHT MEDIATED ORGANOPHOTOREDOX CATALYTIC DEUTERATION OF AROMATIC AND ALIPHATIC ALDEHYDES NATIONAL INSTITUTES OF HEALTH 2023-01-19 US disclosed
US-20220177419-A1 MULTILAYER PHASE DIFFERENCE PLATE, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE ZEON CORPORATION (JP) 2022-06-09 US disclosed
EP-3901156-A1 NITROOXYDERIVATIVE OF ROCK KINASE INHIBITOR Vivavision (Shanghai) Ltd (CN) 2021-10-27 EP disclosed
US-11072634-B2 Inhibitors of transglutaminases ZEDIRA GMBH (DE) 2021-07-27 US disclosed
US-10935835-B2 Optically anisotropic laminate, polarizing plate, and image display device ZEON CORPORATION (JP) 2021-03-02 US disclosed
EP-3783007-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2021-02-24 EP disclosed
US-20170349539-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE ZEON CORPORATION (JP) 2017-12-07 US disclosed
US-20170335193-A1 POLYMERIZABLE COMPOUND, MIXTURE, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC PRODUCT, POLARIZING PLATE, FLAT PANEL DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, AND ANTI-REFLECTION FILM ZEON CORPORATION (JP) 2017-11-23 US disclosed
US-9776954-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic substance ZEON CORPORATION (JP) 2017-10-03 US disclosed
EP-2963068-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY ZEON CORP (JP) 2017-08-23 EP disclosed
US-9695191-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2017-07-04 US disclosed
US-9690022-B2 Liquid crystal composition, phase difference plate, image display device, and method for controlling wavelength dispersion in optically anisotropic layer ZEON CORPORATION (JP) 2017-06-27 US disclosed
US-20170166815-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT ZEON CORPORATION (JP) 2017-06-15 US disclosed
US-20150285979-A1 LIQUID CRYSTAL COMPOSITION, PHASE DIFFERENCE PLATE, IMAGE DISPLAY DEVICE, AND METHOD FOR CONTROLLING WAVELENGTH DISPERSION IN OPTICALLY ANISOTROPIC LAYER ZEON CORPORATION (JP) 2015-10-08 US disclosed
US-20130158044-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-06-20 US disclosed
WO-2012079956-A1 ORGANIC LIGHT-EMITTING COMPONENT, AND USE OF A COPPER COMPLEX IN A CHARGE TRANSPORT LAYER OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same CRY1, CRY2, CCNE2 ALDH1A1 518/4885RAB9A 2481/4885SMN1; SMN2 4489/4885
US-20130158044-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS GRIN2C, TPH1, HTR2C ALDH1A1 418/4885RAB9A 2915/4885SMN1; SMN2 1976/4885
US-12038650-B2 Multilayer phase difference plate, polarizing plate, and image display device RAD1, RPAP1, RPA1 ALDH1A1 4462/4885RAB9A 1715/4885SMN1; SMN2 1172/4885
US-20220177419-A1 MULTILAYER PHASE DIFFERENCE PLATE, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD1, RPAP1, RPA1 ALDH1A1 4472/4885RAB9A 1704/4885SMN1; SMN2 1170/4885
US-20170166815-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT CCNA1, CCNA2, CCNO ALDH1A1 1443/4885RAB9A 3691/4885SMN1; SMN2 2567/4885
US-20230016922-A1 VISIBLE-LIGHT MEDIATED ORGANOPHOTOREDOX CATALYTIC DEUTERATION OF AROMATIC AND ALIPHATIC ALDEHYDES AOX1, TDO2, TALDO1 ALDH1A1 34/4885RAB9A 4302/4885SMN1; SMN2 3267/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH ALDH1A1 603/4885RAB9A 2129/4885SMN1; SMN2 1193/4885
US-20170349539-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE PYM1, CCNB2, CCNT1 ALDH1A1 1453/4885RAB9A 4632/4885SMN1; SMN2 2539/4885
US-11072634-B2 Inhibitors of transglutaminases TGM2, TGM3, TGM1 ALDH1A1 1469/4885RAB9A 1872/4885SMN1; SMN2 3418/4885
US-11647668-B2 Organometallic compound and organic light-emitting device including the same OCIAD1, LEF1, OXA1L ALDH1A1 13/4885RAB9A 3166/4885SMN1; SMN2 4336/4885
US-20170335193-A1 POLYMERIZABLE COMPOUND, MIXTURE, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC PRODUCT, POLARIZING PLATE, FLAT PANEL DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, AND ANTI-REFLECTION FILM NR2E3, NR3C2, NR2C2 ALDH1A1 3033/4885RAB9A 3745/4885SMN1; SMN2 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.