Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitrilotriacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 5/20 | 0.47 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.35 |
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrilotriacetic Acid SCHEMBL213012 | 0.97 | KDM4E (0.56) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL11677912 | 0.97 | KDM4E (0.56) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL31195369 | 0.97 | KDM4E (0.56) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL8633448 | 0.97 | KDM4E (0.56) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL16506703 | 0.97 | KDM4E (0.56) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL11337509 | 0.97 | KDM4E (0.56) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| SCHEMBL1418295 | 0.94 | KDM4E (0.61) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL23358712 | 0.93 | KDM4E (0.52) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL3482707 | 0.93 | KDM4E (0.52) | KDM4EALOX15MAPTSMN1; SMN2CA4 | |
| Nitrilotriacetic Acid SCHEMBL2810628 | 0.93 | KDM4E (0.52) | KDM4EALOX15MAPTSMN1; SMN2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8240 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081911-A | High-stability electroless copper plating solution and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122091808-A | Sodium ion battery sodium supplementing agent and sodium ion battery | — | 2026-05-26 | — | — | CN | claimed |
| CN-122061004-A | Method for recycling ternary cathode material in waste lithium ion battery | 荆门市格林美新材料有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119409896-B | Preparation method and application of ABS grafted latex | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037889-A | Soilless phase drilling fluid and application thereof | 中国石油化工股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037890-A | Drilling composition and application thereof | 中国石油化工股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037894-A | Modified nano-particles and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122038052-A | Desizing and washing composition and preparation method and application thereof | 四川虹基光玻新材料科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122039193-A | Steel mold cleaning agent adopting electrolysis-ultrasonic fusion, application and cleaning method | 广东新球清洗科技股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122012060-A | Alcohol-based chelating acid liquid system and preparation method, use method and application thereof | 中海油田服务股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-3985674-A | BLEACH | VIRGINIA CHEMICALS INC. (US) | 1976-10-12 | — | — | US | claimed |
| US-3982892-A | A HALO-TRIAZINE AND DIALKANOYL DIALKYL GLYOXIME OR TETRAALKANOYL GLYCOLURIL | COLGATE-PALMOLIVE COMPANY (US) | 1976-09-28 | — | — | US | claimed |
| US-3969257-A | Washing and bleaching composition containing bleach, activator and a nitrilotricarboxylic acid compound | COLGATE-PALMOLIVE COMPANY (US) | 1976-07-13 | — | — | US | claimed |
| US-3965026-A | QUATERNARY AMMONIUM, TRISODIUM NITRILOTRIACETATE, ETHYLENE OXIDE-FATTY ALCOHOL ADDUCT | COLGATE-PALMOLIVE COMPANY (US) | 1976-06-22 | — | — | US | claimed |
| US-3954664-A | COPPER SALT AND CYANIDE CONTAINING CATALYST | CONTINENTAL OIL COMPANY (US) | 1976-05-04 | — | — | US | claimed |
| US-3951826-A | All purpose liquid detergent | COLGATE-PALMOLIVE COMPANY (US) | 1976-04-20 | — | — | US | claimed |
| US-3950275-A | SPRAY DRYING, WETTING, COATING | LION FAT & OIL CO., LTD. (JA) | 1976-04-13 | — | — | US | claimed |
| US-3945951-A | ANTIOXIDANTS, SULFIDES, OXY, CARBO | KAO SOAP CO., LTD. (JA) | 1976-03-23 | — | — | US | claimed |
| US-3941723-A | Crystallized alkali metal silicate with sequestering agents | PHILADELPHIA QUARTZ COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-3931360-A | ALKALI METAL NITRILOTRIACETATE | STAUFFER CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | claimed |