Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480554 | 0.79 | GRIN1 (0.39) | GRIN1GRIN2AALDH1A1HTTHRH1 | |
| SCHEMBL9768636 | 0.69 | GRIN1 (0.70) | GRIN1GRIN2AHRH1HTR2ATAAR1 | |
| SCHEMBL12638434 | 0.68 | GRIN1 (0.50) | GRIN1GRIN2AALDH1A1HRH1HTR2A | |
| SCHEMBL11078092 | 0.66 | GRIN1 (0.47) | GRIN1GRIN2AALDH1A1HTR2ASMN1; SMN2 | |
| SCHEMBL11078786 | 0.65 | GABBR2 (0.44) | GRIN1GRIN2AHTR2AAOC3TAAR1 | |
| SCHEMBL9356142 | 0.65 | MMP2 (0.36) | ALDH1A1TAAR1 | |
| SCHEMBL2185597 | 0.65 | KDM4E (0.70) | GRIN1GRIN2AALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL16935732 | 0.65 | GRIN1 (0.48) | GRIN1GRIN2AALDH1A1HRH1HTR2A | |
| SCHEMBL8804694 | 0.64 | GRIN1 (0.44) | GRIN1GRIN2AALDH1A1HRH1HTR2A | |
| SCHEMBL1230770 | 0.64 | GRIN1 (0.41) | GRIN1GRIN2AALDH1A1HRH1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254556-B1 | Semipermeable thin-film membranes comprising siloxane, alkoxysilyl and aryloxysilyl oligomers and copolymers | BEND RES INC (US) | 1994-11-17 | — | — | EP | disclosed |
| US-4781733-A | GAS SEPARATION, POLYCONDENSATION OF POLYFUNCTIONAL COMPOUNDS | BEND RESEARCH, INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0254556-A2 | Semipermeable thin-film membranes comprising siloxane, alkoxysilyl and aryloxysilyl oligomers and copolymers | BEND RESEARCH, INC. (US) | 1988-01-27 | — | — | EP | disclosed |