SCHEMBL9364591

SCHEMBL9364591

C=C1C=Cc2ccccc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
MAPT P10636 4/20 0.61
KDM4E B2RXH2 4/20 0.61
IDO1 P14902 3/20 0.61
LMNA P02545 3/20 0.61
POLB P06746 3/20 0.61
CES1 P23141 3/20 0.61
ALOX15 P16050 3/20 0.61
BCHE P06276 2/20 0.61
PTPRC P08575 2/20 0.61
THRB P10828 2/20 0.61
RECQL P46063 2/20 0.61
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
PKM P14618 1/20 0.61
PTPN1 P18031 1/20 0.61
ACHE P22303 1/20 0.61
HSD17B10 Q99714 1/20 0.61
PTPN22 Q9Y2R2 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867585 0.80 LMNA (0.46) MEN1KMT2AMAPTKDM4EIDO1
SCHEMBL15542936 0.78 LMNA (0.44) MEN1KMT2AMAPTKDM4EIDO1
1,2-Naphthoquinone SCHEMBL173316 0.76 PTPRC (1.00) MEN1KMT2AMAPTKDM4EIDO1
1,2-Naphthoquinone SCHEMBL15167712 0.76 PTPRC (1.00) MEN1KMT2AMAPTKDM4EIDO1
1,2-Naphthoquinone SCHEMBL29363665 0.76 PTPRC (1.00) MEN1KMT2AMAPTKDM4EIDO1
SCHEMBL7721084 0.76 MEN1 (0.67) MEN1KMT2AMAPTKDM4EIDO1
SCHEMBL7721082 0.76 MEN1 (0.67) MEN1KMT2AMAPTKDM4EIDO1
SCHEMBL154778 0.75 ALDH1A1 (0.35) MEN1KMT2AMAPTKDM4EIDO1
1,2-Naphthoquinone SCHEMBL30697786 0.74 PTPRC (0.95) MEN1KMT2AMAPTKDM4EIDO1
1,2-Naphthoquinone SCHEMBL30715501 0.74 PTPRC (0.95) MEN1KMT2AMAPTKDM4EIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006223-A Thermal cracking like fluid coking of feed stock to low boiling EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-04-09 US claimed
JP-6009964-A None JP disclosed
US-12018315-B2 Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-06-25 US disclosed
US-20230242969-A1 PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS HOWARD HUGHES MEDICAL INSTITUTE 2023-08-03 US disclosed
US-11046889-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-06-29 US disclosed
US-10919870-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-02-16 US disclosed
US-10649124-B2 Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film DIC CORPORATION (JP) 2020-05-12 US disclosed
US-20190025490-A1 COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM DIC CORPORATION (JP) 2019-01-24 US disclosed
EP-3346304-A1 COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM DIC Corporation (JP) 2018-07-11 EP disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 US disclosed
US-20170247725-A1 IN VIVO AND IN VITRO OLEFIN CYCLOPROPANATION CATALYZED BY HEME ENZYMES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-08-31 US disclosed
WO-2017079867-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-05-18 WO disclosed
US-9493799-B2 In vivo and in vitro olefin cyclopropanation catalyzed by heme enzymes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-11-15 US disclosed
US-20160248114-A1 QUINONE AND HYDROQUINONE BASED FLOW BATTERY U.S. DEPARTMENT OF ENERGY 2016-08-25 US disclosed
US-20160032330-A1 P-450-CATALYZED ENANTIOSELECTIVE CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-02-04 US disclosed
US-20160002682-A1 IN VIVO AND IN VITRO OLEFIN CYCLOPROPANATION CATALYZED BY HEME ENZYMES UNITED STATES DEPARTMENT OF ENERGY 2016-01-07 US disclosed
WO-2011029752-A1 COMPOSITIONS FOR POLYMER BONDING LOCTITE (R & D) LIMITED (IE) 2011-03-17 WO disclosed
WO-2010106030-A1 OXIDISING AGENTS FOR ELASTOMER BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2010-09-23 WO disclosed
JP-H069964-A THERMAL CONVERSION OF PETROLEUM FEED EXXON RES & ENG CO 1994-01-18 JP disclosed
US-5006223-A Thermal cracking like fluid coking of feed stock to low boiling EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919870-B2 Polymerizable compound and optically anisotropic body ZYX, ZW10, DPY30 MEN1 2026/4885KMT2A 2769/4885MAPT 545/4885
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER SMC4, MAP1LC3C, ZW10 MEN1 1581/4885KMT2A 3183/4885MAPT 27/4885
US-11046889-B2 Polymerizable compound and optically anisotropic body OCIAD1, RCC1, OCIAD2 MEN1 2528/4885KMT2A 4308/4885MAPT 323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.