Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | TDO2 | P48775 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.35 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376612 | 0.89 | PGR (0.43) | IDO1TDO2LMNATP53MAPT | |
| SCHEMBL9773669 | 0.80 | POLB (0.48) | IDO1TDO2TP53MAPTNQO2 | |
| SCHEMBL9375152 | 0.79 | PGR (0.40) | LMNATP53 | |
| SCHEMBL9376526 | 0.76 | MAOB (0.45) | LMNATP53MAPT | |
| SCHEMBL2526545 | 0.73 | CDYL2 (0.52) | LMNATP53MAPTCDYL2CDYL | |
| SCHEMBL9376117 | 0.71 | MAPT (0.40) | IDO1LMNATP53MAPTNQO2 | |
| SCHEMBL7041168 | 0.70 | IDO1 (0.70) | IDO1TDO2MAPTHTR7 | |
| SCHEMBL11093048 | 0.70 | PRKCG (0.36) | TP53PRKCGPRKCBPRKCAPRKCE | |
| SCHEMBL28567244 | 0.69 | CDYL2 (0.51) | TP53MAPTCDYL2CDYLHTR7 | |
| SCHEMBL9834705 | 0.69 | NQO2 (0.39) | IDO1LMNATP53MAPTNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |