Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 2/20 | 0.36 |
| ▸ | PRKCB | P05771 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092619 | 0.75 | ACHE (0.40) | PRKCDACHE | |
| SCHEMBL11089402 | 0.71 | ALDH1A1 (0.38) | PRKCDACHETP53TSHR | |
| SCHEMBL9375554 | 0.70 | IDO1 (0.38) | PRKCGPRKCBPRKCAPRKCEPRKCD | |
| SCHEMBL9376612 | 0.67 | PGR (0.43) | TP53 | |
| SCHEMBL18771239 | 0.65 | HTR2A (0.36) | — | |
| SCHEMBL9375152 | 0.65 | PGR (0.40) | ACHETP53 | |
| SCHEMBL5167531 | 0.65 | PPARA (0.70) | — | |
| SCHEMBL9378781 | 0.64 | MMP13 (0.39) | — | |
| SCHEMBL9670519 | 0.64 | TP53 (0.70) | TP53TSHR | |
| SCHEMBL79521 | 0.64 | TP53 (0.70) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042298-B1 | INDOLE AND INDOLINE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1984-09-12 | — | — | EP | claimed |