Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393750 | 0.80 | OPRM1 (0.52) | HTR7HRH3OPRM1SIGMAR1DRD2 | |
| SCHEMBL7955813 | 0.80 | OPRM1 (0.45) | HTR7ADRA1AHRH3OPRM1SIGMAR1 | |
| SCHEMBL7527316 | 0.75 | CCR1 (0.49) | HTR7ADRA1ACCR1ALDH1A1SIGMAR1 | |
| SCHEMBL7236716 | 0.74 | ADRA1A (0.55) | HTR7ADRA1AHRH3OPRM1SIGMAR1 | |
| SCHEMBL5757125 | 0.72 | SIGMAR1 (0.46) | HRH3OPRM1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL9396649 | 0.72 | ADRA1D (0.43) | HTR7ADRA1AHRH3OPRM1SIGMAR1 | |
| SCHEMBL11740559 | 0.68 | ADRA1A (0.57) | HTR7ADRA1AOPRM1ALDH1A1SIGMAR1 | |
| SCHEMBL3628641 | 0.68 | ADRA1A (0.53) | HTR7ADRA1ACCR1HRH3OPRM1 | |
| SCHEMBL10650461 | 0.68 | TBXAS1 (0.52) | — | |
| SCHEMBL82726 | 0.68 | DRD2 (0.62) | ADRA1ADRD2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022829-A2 | DIHYDROPYRIDINES AND NEW USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1994-10-13 | — | — | WO | disclosed |