SCHEMBL9399197

SCHEMBL9399197

Cn1c(=S)n(C)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.50
ALDH1A1 P00352 4/20 0.50
GPR3 P46089 1/20 0.50
RXFP1 Q9HBX9 2/20 0.48
PSMB8 P28062 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
EGFR P00533 1/20 0.45
KDM4E B2RXH2 1/20 0.43
HTT P42858 1/20 0.40
CA12 O43570 2/20 0.39
CA9 Q16790 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
BRD4 O60885 1/20 0.39
BRPF1 P55201 1/20 0.39
KAT2B Q92831 1/20 0.39
BRD9 Q9H8M2 1/20 0.39
APEX1 P27695 1/20 0.39
BRD2 P25440 1/20 0.38
TSHR P16473 1/20 0.38
F12 P00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18353634 0.79 ALDH1A1 (0.47) MAPTALDH1A1GPR3RXFP1PSMB8
SCHEMBL9150234 0.78 ERCC1 (0.55) MAPTALDH1A1GPR3NPSR1KDM4E
SCHEMBL19411184 0.76 BRD2 (0.46) MAPTALDH1A1GPR3RXFP1PSMB8
SCHEMBL19411185 0.76 APEX1 (0.49) MAPTALDH1A1NPSR1HTTAPEX1
SCHEMBL12122685 0.75 PGR (0.47) ALDH1A1KDM4EHTTSMN1; SMN2APEX1
SCHEMBL19411205 0.73 RAB9A (0.55) ALDH1A1KDM4ESMN1; SMN2APEX1BRD2
SCHEMBL10014869 0.73 GPR3 (0.60) MAPTALDH1A1GPR3RXFP1PSMB8
SCHEMBL3233843 0.73 GPR3 (0.52) MAPTALDH1A1GPR3RXFP1PSMB8
SCHEMBL12122684 0.72 TLR8 (0.49) MAPTALDH1A1KDM4EHTTSMN1; SMN2
SCHEMBL12122686 0.72 TLR8 (0.49) MAPTALDH1A1KDM4EHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119789670-A Perovskite solar cell and preparation method thereof 中建科工集团有限公司 2025-04-08 CN claimed
CN-119789670-A Perovskite solar cell and preparation method thereof 中建科工集团有限公司 2025-04-08 CN disclosed
US-20170001983-A1 TRPA1 MODULATORS ALGOMEDIX, INC. 2017-01-05 US disclosed
US-8057780-B2 Method for preparing nanoparticles using carbene derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-11-15 US disclosed
US-8057780-B2 Method for preparing nanoparticles using carbene derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-11-15 US disclosed
US-20090289233-A1 METHOD FOR PREPARING NANOPARTICLES USING CARBENE DERIVATIVES SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-11-26 US disclosed
US-20090289233-A1 METHOD FOR PREPARING NANOPARTICLES USING CARBENE DERIVATIVES SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-11-26 US disclosed
US-7348296-B2 Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2008-03-25 US disclosed
US-7348296-B2 Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2008-03-25 US disclosed
US-5371102-A N,n-disubstituted thiocarbamide UNIVERSITY OF HAWAII (US) 1994-12-06 US disclosed
US-4216284-A NONDIFFUSIBLE SILVER BLEACH INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1980-08-05 US disclosed
US-4001020-A DEVELOPING A SILVER HA1IDE EMULSION IN CONTACT WITH A HETEROCYCLIC THIONE AND A POLYALKYLENE OXIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-01-04 US disclosed
US-3954474-A SILVER HALIDE EMULSION; ALDEHYDE TYPE HARDENER FUJI PHOTO FILM CO., LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170001983-A1 TRPA1 MODULATORS TRPA1, TRPV1, TRPV2 MAPT 996/4885ALDH1A1 1436/4885GPR3 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.