Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708258 | 0.92 | MAPT (0.43) | SMN1; SMN2LMNAMAPTALDH1A1POLB | |
| SCHEMBL9708256 | 0.91 | HPGD (0.44) | — | |
| SCHEMBL9708690 | 0.91 | MAPT (0.42) | MAPTALDH1A1DPP4BRAF | |
| SCHEMBL9707504 | 0.90 | ALDH1A1 (0.42) | ALOX15HSD17B10SMN1; SMN2LMNAMAPT | |
| SCHEMBL9707766 | 0.90 | ALDH1A1 (0.42) | ALOX15HSD17B10SMN1; SMN2LMNAMAPT | |
| SCHEMBL9708836 | 0.89 | HPGD (0.47) | ALOX15HSD17B10SMN1; SMN2LMNAMAPT | |
| SCHEMBL9708624 | 0.89 | PDE1A (0.44) | SMN1; SMN2LMNAALDH1A1NPSR1TSHR | |
| SCHEMBL9708614 | 0.89 | POLB (0.46) | ALOX15HSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL9708813 | 0.89 | RAB9A (0.44) | SMN1; SMN2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL9707699 | 0.89 | ALOX15 (0.52) | ALOX15HSD17B10SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |