Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402963 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10LMNAALOX15 | |
| SCHEMBL9184350 | 0.76 | MAPT (0.44) | ALDH1A1ALOX15GAARAB9ANPC1 | |
| SCHEMBL10432594 | 0.72 | NPC1 (0.39) | ALDH1A1MAPK1HSD17B10LMNAALOX15 | |
| SCHEMBL10031827 | 0.71 | PGR (0.47) | ALDH1A1MAPK1LMNACA2HDAC1 | |
| SCHEMBL6919651 | 0.70 | CA1 (0.59) | ALDH1A1TDP1RAB9ANPC1MAPT | |
| SCHEMBL5972998 | 0.70 | MAPT (0.53) | ALDH1A1TDP1GAARAB9ANPC1 | |
| SCHEMBL9781221 | 0.69 | MPO (0.57) | ALDH1A1MAPK1LMNAMAPTCA1 | |
| SCHEMBL11828224 | 0.69 | GSK3B (0.61) | ALDH1A1MAPK1HSD17B10LMNAALOX15 | |
| SCHEMBL9402745 | 0.67 | TDP1 (0.44) | ALDH1A1LMNATDP1RAB9AMAPT | |
| SCHEMBL9402878 | 0.67 | KMT2A (0.49) | ALDH1A1RAB9ANPC1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |