Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184350 | 0.82 | MAPT (0.44) | ALDH1A1ALOX15NPC1RAB9AMAPT | |
| SCHEMBL27908475 | 0.81 | CA12 (0.52) | ALDH1A1APEX1RECQLTDP1NPC1 | |
| SCHEMBL9402546 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL27908329 | 0.79 | GSK3B (0.50) | ALDH1A1LMNAMAPK1RECQLNPC1 | |
| SCHEMBL27908332 | 0.76 | PLOD2 (0.55) | ALDH1A1LMNAKMT2AMMP1 | |
| SCHEMBL10432594 | 0.74 | NPC1 (0.39) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL10031827 | 0.73 | PGR (0.47) | ALDH1A1LMNAMAPK1HDAC1CA2 | |
| SCHEMBL6919651 | 0.72 | CA1 (0.59) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL5972998 | 0.72 | MAPT (0.53) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL9402745 | 0.72 | TDP1 (0.44) | ALDH1A1LMNATDP1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |