SCHEMBL9403989

SCHEMBL9403989

[N-]=[N+]=C(C(=O)CCc1ccc(S(=O)(=O)Cl)c2ccccc12)C(=O)CCc1ccc(S(=O)(=O)Cl)c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.34
NFE2L2 Q16236 2/20 0.34
FABP4 P15090 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9404027 0.84 KEAP1 (0.39) KEAP1NFE2L2FABP4
SCHEMBL9404021 0.75 GPR84 (0.49) GPR84
SCHEMBL7002514 0.73 RAD52 (0.43) KEAP1NFE2L2
SCHEMBL314045 0.72 LDHA (0.33) GPR84
Potassium Ion SCHEMBL7808419 0.70 RAD52 (0.38) KEAP1NFE2L2
SCHEMBL1595970 0.70 LDHA (0.36) FABP4APEX1
SCHEMBL4642257 0.70 LDHA (0.36)
SCHEMBL456926 0.70 ALDH1A1 (0.44)
SCHEMBL9404002 0.69 PLAAT3 (0.37)
SCHEMBL9165551 0.69 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323050-B1 Photosensitive compound WAKO PURE CHEM IND LTD (JP) 1994-11-02 EP disclosed
US-5250669-A Thermostability, photoresists WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-05 US disclosed
EP-0323050-A2 Photosensitive compound WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1989-07-05 EP disclosed