Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404276 | 0.86 | PRMT5 (0.34) | — | |
| SCHEMBL9404358 | 0.84 | PPARA (0.37) | — | |
| SCHEMBL9404487 | 0.82 | P2RX7 (0.36) | POLB | |
| SCHEMBL9404357 | 0.77 | USP30 (0.41) | USP30CHRNB2CHRNA4POLBLMNA | |
| Oxalic Acid SCHEMBL9404430 | 0.72 | CHRNB2 (0.43) | USP30CHRNB2CHRNA4POLBLMNA | |
| Oxalic Acid SCHEMBL9404275 | 0.68 | CHRM2 (0.42) | LMNA | |
| SCHEMBL9404481 | 0.63 | CHRM1 (0.41) | — | |
| SCHEMBL9404483 | 0.61 | MAPT (0.34) | CHRNB2CHRNA4POLB | |
| SCHEMBL9232450 | 0.60 | ALDH1A1 (0.40) | POLBLMNA | |
| SCHEMBL20031303 | 0.57 | NOTUM (0.62) | POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356912-A | 3-(5-isoxazolyl)-1-methyl-1,2,3,6-tetrahydropyridine useful for treating Alzheimer's disease | NOVO NORDISK A/S (DK) | 1994-10-18 | — | — | US | disclosed |
| US-5262427-A | Cognition activators for Alzheimer*s disease | NOVO NORDISK A/S (DK) | 1993-11-16 | — | — | US | disclosed |
| EP-0316718-A2 | Azacyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-05-24 | — | — | EP | disclosed |