Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416939 | 0.90 | PTGS2 (0.37) | OPRM1OPRD1OPRK1ALOX5PTGS1 | |
| SCHEMBL9417080 | 0.87 | PTGS2 (0.38) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9416986 | 0.84 | HTT (0.41) | OPRM1OPRD1OPRK1ALOX5PTGS1 | |
| SCHEMBL9416974 | 0.81 | ALOX5 (0.32) | OPRK1HDAC1ALOX5PTGS1PTGS2 | |
| SCHEMBL9417050 | 0.81 | ALDH1A1 (0.39) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9417069 | 0.81 | KDM4E (0.43) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9417011 | 0.81 | DRD2 (0.40) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL9417022 | 0.79 | PTGS2 (0.33) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9417007 | 0.78 | KDM4E (0.36) | ALOX5PTGS1PTGS2APP | |
| SCHEMBL9417117 | 0.76 | ALOX5 (0.32) | OPRM1ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |