Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110163 | 0.73 | — | — | |
| SCHEMBL7108596 | 0.71 | KEAP1 (0.34) | — | |
| SCHEMBL7087009 | 0.69 | TACR1 (0.38) | ALDH1A1 | |
| SCHEMBL7464033 | 0.67 | RBP4 (0.44) | RBP4KDM4EALDH1A1 | |
| SCHEMBL7081979 | 0.66 | ACLY (0.38) | NPSR1ALDH1A1 | |
| SCHEMBL7088314 | 0.65 | LMNA (0.35) | ALDH1A1 | |
| SCHEMBL7085267 | 0.64 | ALDH1A1 (0.36) | RBP4CYP1A2ALDH1A1 | |
| SCHEMBL7084831 | 0.64 | LMNA (0.35) | — | |
| SCHEMBL9359388 | 0.64 | CA2 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL27564761 | 0.64 | ESR1 (0.42) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992008693-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |