Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 10/20 | 0.40 |
| ▸ | HRH2 | P25021 | 4/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428870 | 0.85 | HRH3 (0.57) | MEN1ALDH1A1KMT2AHRH3HRH1 | |
| SCHEMBL9429616 | 0.82 | HRH3 (0.58) | MEN1ALDH1A1KMT2AHRH3HRH1 | |
| SCHEMBL9428883 | 0.82 | HRH1 (0.50) | MEN1ALDH1A1KMT2AHRH3HRH1 | |
| SCHEMBL9386451 | 0.82 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AHRH3HRH1 | |
| Hydrochloric Acid SCHEMBL9386358 | 0.81 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2AHRH3HRH1 | |
| SCHEMBL9429324 | 0.81 | DRD2 (0.56) | HRH3HRH1HRH2HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9428228 | 0.80 | SIGMAR1 (0.55) | HRH3HRH1HRH2HTR1ADRD2 | |
| SCHEMBL9428720 | 0.79 | MEN1 (0.50) | MEN1ALDH1A1KMT2AHRH3HRH1 | |
| SCHEMBL9428375 | 0.79 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AADRA1AHTR1A | |
| SCHEMBL9428864 | 0.79 | KDM4E (0.57) | MEN1ALDH1A1KMT2AHRH1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |