Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428502 | 0.85 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL9386345 | 0.84 | DRD2 (0.51) | DRD2DRD4DRD3ALDH1A1MAPT | |
| SCHEMBL9385003 | 0.82 | PKM (0.52) | DRD2DRD4DRD3HRH2HRH1 | |
| SCHEMBL9429147 | 0.78 | SCN8A (0.38) | DRD4CYP19A1CACNA1BHRH3POLB | |
| SCHEMBL9428964 | 0.77 | MAPK1 (0.49) | RXFP1MMP3DRD2DRD4DRD3 | |
| SCHEMBL9428388 | 0.72 | CYP1A2 (0.49) | RXFP1MMP3DRD2DRD3HRH1 | |
| SCHEMBL9428759 | 0.71 | ADRB2 (0.38) | RXFP1ALDH1A1HPGD | |
| SCHEMBL1715002 | 0.71 | MMP3 (0.55) | MMP2MMP3DRD2DRD4DRD3 | |
| SCHEMBL8780756 | 0.69 | ADORA3 (0.40) | RXFP1MMP2MMP3CYP19A1MAPT | |
| SCHEMBL1714696 | 0.69 | DRD4 (0.58) | MMP3DRD2DRD4DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |