Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenazine SCHEMBL10876543 | 0.88 | MAPT (0.50) | ALDH1A1HPGDMAPTKDM4ENQO2 | |
| Phenazine SCHEMBL94396 | 0.88 | MAPT (0.50) | ALDH1A1HPGDMAPTKDM4ENQO2 | |
| Phenazine SCHEMBL2873102 | 0.88 | MAPT (0.50) | ALDH1A1HPGDMAPTKDM4ENQO2 | |
| Acridine SCHEMBL8000372 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL11600717 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL10831095 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HPGDGLAMAPTACHE | |
| Anthracene SCHEMBL31722820 | 0.86 | CYP1A2 (0.43) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL28146547 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDGLAMAPTACHE | |
| Naphthalene SCHEMBL28586134 | 0.81 | CYP2A6 (0.42) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL3656264 | 0.80 | CYP1A2 (0.41) | ALDH1A1HPGDMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118879786-B | Application of RHPS4 in monascus fermentation to produce monascus pigment and application of monascus fermentation liquid | 武汉轻工大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118879786-A | Application of RHPS4 in monascus fermentation to produce monascus pigment and application of monascus fermentation liquid | 武汉轻工大学 | 2024-11-01 | — | — | CN | claimed |
| CN-118879786-B | Application of RHPS4 in monascus fermentation to produce monascus pigment and application of monascus fermentation liquid | 武汉轻工大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118879786-B | Application of RHPS4 in monascus fermentation to produce monascus pigment and application of monascus fermentation liquid | 武汉轻工大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118879786-A | Application of RHPS4 in monascus fermentation to produce monascus pigment and application of monascus fermentation liquid | 武汉轻工大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-118879786-A | Application of RHPS4 in monascus fermentation to produce monascus pigment and application of monascus fermentation liquid | 武汉轻工大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-114712355-B | Application of RHPS4 in preparation of medicines for inhibiting staphylococcus aureus and pseudomonas aeruginosa | 武汉轻工大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114712355-A | Application of RHPS4 in preparation of medicine for inhibiting human pathogenic bacteria and medicine thereof | 武汉轻工大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114712355-A | Application of RHPS4 in preparation of medicine for inhibiting human pathogenic bacteria and medicine thereof | 武汉轻工大学 | 2022-07-08 | — | — | CN | disclosed |
| EP-2251003-A2 | Ophthalmic Compositions for the Re-epithelialization, Healing and Disinfection of the Eye Tissues | Bruschettini S.r.l. (IT) | 2010-11-17 | — | — | EP | disclosed |