SCHEMBL944591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL942801	0.79	HTR2A (0.46)	C5AR1HTR2AHTR2CMCOLN3HSD11B1
	SCHEMBL944589	0.77	C5AR1 (0.75)	C5AR1MCOLN3LMNATSHRHTT
	SCHEMBL943729	0.77	TEAD1 (0.43)	LMNAMAPTL3MBTL1HCRTR2ALDH1A1
	SCHEMBL945294	0.75	L3MBTL1 (0.50)	C5AR1TSHRMAPTL3MBTL1ALDH1A1
	SCHEMBL3822613	0.74	MCOLN3 (0.60)	HTR2AHTR2CMCOLN3TSHRHTT
	SCHEMBL701463	0.73	ALDH1A1 (0.55)	HTR2AHTR2CHSD11B1LMNAHTT
	Hydrochloric Acid SCHEMBL5808143	0.73	MCOLN3 (0.58)	HTR2AHTR2CMCOLN3TSHRHTT
	SCHEMBL15756414	0.72	MCOLN3 (0.54)	C5AR1HTR2AHTR2CMCOLN3HSD11B1
	SCHEMBL945401	0.72	ALDH1A1 (0.45)	MCOLN3HSD11B1LMNAHTTMAPT
	SCHEMBL7972381	0.70	HTR2A (0.49)	C5AR1HTR2AHTR2CHSD11B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.