SCHEMBL945401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL475089	0.85	ALDH1A1 (0.55)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	SCHEMBL29468592	0.85	ALDH1A1 (0.55)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	SCHEMBL18697270	0.82	L3MBTL1 (0.43)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	SCHEMBL945402	0.77	GAA (0.54)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	SCHEMBL27623150	0.77	ALDH1A1 (0.49)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	SCHEMBL9634830	0.75	KMT2A (0.51)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	(Phenylsulfonyl)Benzene SCHEMBL10595193	0.75	HTR6 (0.61)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1
	SCHEMBL943160	0.75	HTR6 (0.55)	ALDH1A1KDM4EHTTNPSR1GAA
	SCHEMBL942877	0.74	G6PD (0.39)	L3MBTL1HSD11B1MAPTNPSR1GAA
	SCHEMBL944800	0.73	ALDH1A1 (0.46)	ALDH1A1KDM4EHTTL3MBTL1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.