Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787174 | 0.90 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9446203 | 0.86 | NOS1 (0.42) | TSHR | |
| SCHEMBL2388264 | 0.84 | ENPP2 (0.44) | SIGMAR1 | |
| SCHEMBL11330980 | 0.84 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL9446165 | 0.81 | ALDH1A1 (0.49) | SIGMAR1TSHR | |
| SCHEMBL14459615 | 0.80 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL14368015 | 0.79 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL11732126 | 0.78 | ALOX15 (0.43) | SIGMAR1TSHR | |
| SCHEMBL8095675 | 0.78 | HTR7 (0.47) | SIGMAR1TP53 | |
| SCHEMBL5145010 | 0.78 | ALDH1A1 (0.59) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250420-A | Using an electron carrier | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0285998-B1 | METHOD AND REAGENT FOR DETERMINATION OF DEHYDROGENASE OR ITS SUBSTRATE | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0285998-A2 | Method and reagent for determination of dehydrogenase or its substrate | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4251629-A | COLORIMETRY, USING 4-AMINOANTIPYRENE, N-SUBSTITUTED ANILINE, ACTIVATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |