Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449807 | 0.88 | DRD2 (0.46) | ADRA1AHTR1ADRD2HTR2ADRD3 | |
| SCHEMBL9449660 | 0.80 | HTR1A (0.47) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL7759823 | 0.80 | SIGMAR1 (0.48) | ADRA1DADRA1AADRA1BPOLBHTR1A | |
| Hydrochloric Acid SCHEMBL9449688 | 0.78 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9449928 | 0.77 | HTR1A (0.51) | ADRA1DADRA1AADRA1BPOLBHTR1A | |
| SCHEMBL9449597 | 0.76 | SIGMAR1 (0.55) | HTR1A | |
| SCHEMBL8109164 | 0.75 | SIGMAR1 (0.51) | ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL8108851 | 0.74 | CCR3 (0.59) | HTR1AKCNH2SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL9437976 | 0.73 | HTR1A (0.60) | HTR1ADRD2HTR2AALDH1A1HTR2C | |
| SCHEMBL7756765 | 0.73 | SIGMAR1 (0.58) | POLBHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | disclosed |