Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663667 | 0.87 | ALDH1A1 (0.60) | ALDH1A1RECQLPOLBGAASMN1; SMN2 | |
| SCHEMBL14004242 | 0.83 | ALDH1A1 (0.56) | ALDH1A1RECQLPOLBGAASMN1; SMN2 | |
| Sulfamate SCHEMBL9451342 | 0.82 | MAPT (0.49) | CA1CA2CA9CA12CA7 | |
| Sulfamate SCHEMBL9451320 | 0.82 | L3MBTL1 (0.51) | CA1CA2CA9CA12CA7 | |
| 2-(4-Chlorphenoxy)-Ethanol SCHEMBL9451335 | 0.82 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| Phenoxyethanol SCHEMBL9451237 | 0.81 | ALDH1A1 (0.73) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4687161 | 0.79 | ALOX15 (0.52) | ALDH1A1RECQLPOLBGAASMN1; SMN2 | |
| SCHEMBL25279717 | 0.79 | GAA (0.72) | POLBGAALMNARAB9ANR1I2 | |
| SCHEMBL9043824 | 0.78 | CA2 (0.68) | CA1CA2CA9CA12CA7 | |
| SCHEMBL20128986 | 0.77 | APP (0.59) | ALDH1A1RECQLPOLBSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |