SCHEMBL663667

SCHEMBL663667

OCCOc1ccc(Br)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
RECQL P46063 1/20 0.60
NR1I2 O75469 1/20 0.53
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
CYP3A4 P08684 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KDM4E B2RXH2 1/20 0.48
DRD4 P21917 2/20 0.47
DRD2 P14416 1/20 0.47
DRD3 P35462 1/20 0.47
LSS P48449 1/20 0.46
MAOB P27338 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
APP P05067 1/20 0.46
LTA4H P09960 1/20 0.46
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14004242 0.96 ALDH1A1 (0.56) ALDH1A1RECQLNR1I2POLBGAA
SCHEMBL4687161 0.92 ALOX15 (0.52) ALDH1A1RECQLNR1I2POLBGAA
SCHEMBL21876548 0.89 APP (0.59) ALDH1A1RECQLPOLBCYP3A4SMN1; SMN2
SCHEMBL20128986 0.89 APP (0.59) ALDH1A1RECQLPOLBCYP3A4SMN1; SMN2
SCHEMBL20294645 0.89 APP (0.59) ALDH1A1RECQLPOLBCYP3A4SMN1; SMN2
SCHEMBL15786150 0.89 APP (0.59) ALDH1A1RECQLPOLBCYP3A4SMN1; SMN2
SCHEMBL14211670 0.89 APP (0.59) ALDH1A1RECQLPOLBCYP3A4SMN1; SMN2
SCHEMBL577534 0.88 LSS (0.53) ALDH1A1RECQLPOLBKDM4EDRD4
SCHEMBL28106819 0.87 ALDH1A1 (0.75) ALDH1A1RECQLNR1I2GAACYP3A4
SCHEMBL48239 0.87 ALDH1A1 (0.75) ALDH1A1RECQLNR1I2GAACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292417-A Process for producing carboxylic acid 赣南医学院 2021-08-24 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
WO-2025242566-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR THE PREVENTION OR TREATMENT OF DISEASES OF THE CNS Samsara Therapeutics Inc. (US) 2025-11-27 WO disclosed
EP-4653430-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR THE PREVENTION OR TREATMENT OF DISEASES OF THE CNS Samsara Therapeutics Inc. (US) 2025-11-26 EP disclosed
US-12479849-B2 EGFR inhibitors for the treatment of cancer HOFFMANN-LA ROCHE INC. (US) 2025-11-25 US disclosed
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND SHOUYAO HOLDINGS BEIJING CO LTD (CN) 2025-07-10 US disclosed
US-12325708-B2 Adenosine 2 receptor antagonists NEKTAR THERAPEUTICS (US) 2025-06-10 US disclosed
EP-4373817-B1 SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2025-05-21 EP disclosed
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-04-10 US disclosed
EP-4501912-A1 NOVEL HETEROCYCLIC COMPOUND Shouyao Holdings (Beijing) Co., Ltd. (CN) 2025-02-05 EP disclosed
EP-0403185-A2 Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals A.H. ROBINS COMPANY, INCORPORATED (US) 1990-12-19 EP disclosed
EP-0399635-A2 Alkaline phenolic resole resin binders BORDEN, INC. (US) 1990-11-28 EP disclosed
US-4971132-A Production of foundry molds and cores, placing a resole resin and refractory binder in a mold, gassing with a volatile ester ACME RESIN CORPORATION (US) 1990-11-20 US disclosed
EP-0389082-A2 Alkaline benzylic ether phenolic resin binders BORDEN, INC. (US) 1990-09-26 EP disclosed
US-4946759-A CLEAVAGE PRODUCT UNDER THE ACTION OF ACTINIC RADIATION HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-07 US disclosed
US-4929648-A FOUNDRIES, MOLDINGS ACME RESIN CORPORATION (US) 1990-05-29 US disclosed
EP-0315748-A2 Positive-working radiation-sensitive composistion and radiation-sensitive recording material produced therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-17 EP disclosed
US-4359424-A Substituted phenoxyethoxytetrahydropyran ZOECON CORPORATION (US) 1982-11-16 US disclosed
US-4304924-A Cyclopropylmethyl benzoates ZOECON CORPORATION (US) 1981-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 ALDH1A1 4449/4885RECQL 4032/4885NR1I2 2042/4885
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND MAPT, MNAT1, MAT2A ALDH1A1 996/4885RECQL 1404/4885NR1I2 247/4885
US-12325708-B2 Adenosine 2 receptor antagonists ADORA2A, ADORA2B, ADORA3 ALDH1A1 1202/4885RECQL 633/4885NR1I2 2240/4885
US-12479849-B2 EGFR inhibitors for the treatment of cancer EGFR, ERBB2, ERBB3 ALDH1A1 4090/4885RECQL 3088/4885NR1I2 789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.