Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL28633653 | 1.00 | — | — | |
| SCHEMBL126 | 0.82 | — | — | |
| SCHEMBL5438089 | 0.82 | — | — | |
| SCHEMBL11523834 | 0.82 | — | — | |
| SCHEMBL5728116 | 0.82 | — | — | |
| SCHEMBL3093207 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHR | |
| Cyclohexane SCHEMBL29188796 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNA | |
| Cyclopentane SCHEMBL20394153 | 0.76 | — | — | |
| Cyclohexane SCHEMBL457847 | 0.76 | LMNA (0.57) | ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL22394670 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117142991-A | Method for preparing polyol carboxylic acid ester, polymerizable composition and adhesive | 益丰新材料股份有限公司 | 2023-12-01 | — | — | CN | claimed |
| US-7485663-B2 | Carvedilol | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-02-03 | — | — | US | claimed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| US-20040225132-A1 | Carvedilol | HILDESHEIM JEAN (IL) | 2004-11-11 | — | — | US | claimed |
| US-20020143045-A1 | Carvedilol | TEVA PHARMACEUTICALS USA, INC. | 2002-10-03 | — | — | US | claimed |
| CN-117142991-A | Method for preparing polyol carboxylic acid ester, polymerizable composition and adhesive | 益丰新材料股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2011051975-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PURE EPROSARTANAND ITS PHARMACEUTICAL ACCEPTABLE SALTS | MATRIX LABORATORIES LTD (IN) | 2011-05-05 | — | — | WO | disclosed |
| US-20110054186-A1 | PROCESS FOR EPROSARTAN INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2011-03-03 | — | — | US | disclosed |
| WO-2011004384-A2 | PROCESS FOR THE PREPARATION OF EPROSARTAN | GLOCHEM INDUSTRIES LIMITED (IN) | 2011-01-13 | — | — | WO | disclosed |
| EP-2257540-A2 | IMPROVED PROCESS FOR EPROSARTAN INTERMEDIATE | Hetero Research Foundation (IN) | 2010-12-08 | — | — | EP | disclosed |
| US-20100137613-A1 | PROCESS FOR EPROSARTAN | HETERO DRUGS LIMITED (IN) | 2010-06-03 | — | — | US | disclosed |
| WO-2010023688-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF EPROSARTAN | MATRIX LABORATORIES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |
| US-6699997-B2 | REACTING 4-(OXIRAN-2-YLMETHOXY)-9H- CARBAZOLE WITH 2-(2-METHOXYPHENOXY)ETHYLAMINE TO PRODUCE CARVEDILOL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-03-02 | — | — | US | disclosed |
| US-20020143045-A1 | Carvedilol | TEVA PHARMACEUTICALS USA, INC. | 2002-10-03 | — | — | US | disclosed |
| EP-0970073-A4 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2001-01-24 | — | — | EP | disclosed |
| US-6172237-B1 | Process for preparing eprosartan | SMITHKLINE BEECHAM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-0970073-A1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035963-A1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |
| US-5773592-A | COMPRISES A CHEMILUMINESCENT MOIETY, A PHOTOCHROMIC MOIETY AND A BIOLOGICALLY ACTIVE AGENT CAPABLE OF BEING RELEASED | MILLS RANDELL LEE (US) | 1998-06-30 | — | — | US | disclosed |
| US-5428163-A | Luminides; chemiluminescence; redox system, releasing free drug | MILLS RANDELL L (US) | 1995-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | APEH, PAH, ALAD | ALDH1A1 61/4885TSHR 3654/4885TDP1 2098/4885 |
| US-20110054186-A1 | PROCESS FOR EPROSARTAN INTERMEDIATE | PTGER1, PTGER4, PDGFRA | ALDH1A1 761/4885TSHR 226/4885TDP1 2656/4885 |
| US-20100137613-A1 | PROCESS FOR EPROSARTAN | PTMA, PTGER1, PDGFRA | ALDH1A1 732/4885TSHR 453/4885TDP1 2935/4885 |
| US-20040225132-A1 | Carvedilol | REN, ADRB1, ADRB2 | ALDH1A1 1694/4885TSHR 3165/4885TDP1 4010/4885 |
| US-20020143045-A1 | Carvedilol | REN, ADRB1, ADRB2 | ALDH1A1 1694/4885TSHR 3165/4885TDP1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.