Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645653 | 0.84 | APP (0.48) | L3MBTL1GAAMEN1KMT2AALOX5 | |
| SCHEMBL9645861 | 0.81 | GRM5 (0.40) | L3MBTL1ALOX5NPC1RAB9A | |
| SCHEMBL27379105 | 0.74 | L3MBTL1 (0.86) | L3MBTL1GAAACHEDDB1CRBN | |
| SCHEMBL180739 | 0.74 | L3MBTL1 (0.86) | L3MBTL1GAAACHEDDB1CRBN | |
| SCHEMBL9645280 | 0.74 | HTT (0.44) | L3MBTL1GAAMEN1KMT2ANPC1 | |
| SCHEMBL2859977 | 0.73 | SIGMAR1 (0.56) | L3MBTL1DRD4ACHESIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL6818365 | 0.73 | L3MBTL1 (0.83) | L3MBTL1GAAACHEDDB1CRBN | |
| SCHEMBL9465620 | 0.72 | PRKCA (0.40) | L3MBTL1DDB1CRBNPOLBMEN1 | |
| SCHEMBL9453365 | 0.71 | MEN1 (0.38) | L3MBTL1DDB1CRBNMEN1KMT2A | |
| Bicarbonate SCHEMBL5329298 | 0.70 | L3MBTL1 (0.78) | L3MBTL1GAAACHEDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |