Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 14/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466921 | 0.75 | CNR2 (0.51) | CNR2RXRARXRBRXRGMALT1 | |
| SCHEMBL9520169 | 0.75 | RXRA (0.56) | CNR2RXRARXRBRXRGMALT1 | |
| SCHEMBL9466137 | 0.74 | CNR2 (0.46) | CNR2RXRARXRBRXRGMALT1 | |
| SCHEMBL9466275 | 0.74 | ALOX5 (0.50) | CNR2RXRARXRBRXRGMALT1 | |
| SCHEMBL5387633 | 0.72 | PTGS2 (0.69) | RXRARXRBRXRGMALT1PTGS2 | |
| SCHEMBL5416591 | 0.70 | PTGS2 (0.60) | RXRARXRBRXRGMALT1PTGS2 | |
| SCHEMBL3237716 | 0.70 | CNR2 (0.45) | CNR2RXRARXRBRXRGMALT1 | |
| SCHEMBL9465750 | 0.69 | CNR2 (0.43) | CNR2RXRARXRBRXRGMALT1 | |
| SCHEMBL9466821 | 0.68 | PTGS2 (0.47) | CNR2RXRARXRBRXRGPTGS2 | |
| SCHEMBL9466824 | 0.67 | ALDH1A1 (0.45) | CNR2MALT1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242940-A | Antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |