Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828397 | 0.88 | L3MBTL1 (0.60) | KDM4EHPGDALDH1A1HTR2AHTR2C | |
| SCHEMBL9045792 | 0.83 | L3MBTL1 (0.53) | KDM4EHPGDALDH1A1HTR2AHTR2C | |
| SCHEMBL9047228 | 0.83 | TRPM8 (0.45) | KDM4EHPGDALDH1A1HTR2AHTR2C | |
| SCHEMBL8828362 | 0.80 | LMNA (0.59) | HPGDALDH1A1GAASMN1; SMN2MTNR1A | |
| SCHEMBL8828168 | 0.78 | DRD3 (0.45) | KDM4EMTNR1AMTNR1B | |
| SCHEMBL8828131 | 0.77 | CYP3A4 (0.52) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL8828277 | 0.76 | KDM4E (0.66) | KDM4EHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8828285 | 0.76 | NOS2 (0.46) | KDM4EHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8828235 | 0.76 | MAPT (0.56) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9158719 | 0.75 | DRD3 (0.46) | KDM4EMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |