Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568787 | 0.82 | HSD11B1 (0.46) | ALDH1A1LMNAMGLLCYP1A2TSHR | |
| SCHEMBL9568778 | 0.81 | SIGMAR1 (0.38) | MGLL | |
| SCHEMBL9568762 | 0.76 | POLB (0.51) | ALDH1A1HPGDKDM4EMAPTSLC6A3 | |
| SCHEMBL7114830 | 0.73 | BRD4 (0.40) | KDM4EMAPTMGLLHSD17B10 | |
| SCHEMBL9469004 | 0.73 | TDP1 (0.42) | ALDH1A1KDM4ELMNAMAPTMAPK10 | |
| SCHEMBL9469451 | 0.72 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ELMNAMAPK10 | |
| SCHEMBL9542013 | 0.71 | TSHR (0.46) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL8791363 | 0.71 | NQO2 (0.42) | ALDH1A1HPGDKDM4EMAPTMGLL | |
| SCHEMBL8790766 | 0.70 | KMT2A (0.48) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL8791403 | 0.70 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| US-5252592-A | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |