SCHEMBL94773

SCHEMBL94773

Nc1nc(S)nc2[nH]cnc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.33
PDPK1 O15530 1/20 0.33
XDH P47989 2/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
HPGD P15428 1/20 0.31
PTGS1 P23219 1/20 0.31
MAPK3 P27361 1/20 0.31
HBB P68871 1/20 0.31
PAX8 Q06710 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PNP P00491 1/20 0.31
LMNA P02545 1/20 0.31
DRD3 P35462 1/20 0.31
PI4KA P42356 1/20 0.31
LRRK2 Q5S007 1/20 0.31
PI4K2B Q8TCG2 1/20 0.31
PI4K2A Q9BTU6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Diaminopurine SCHEMBL24052 0.79 GDA (0.48) GDAPDPK1XDHUSP2ALDH1A1
SCHEMBL1275415 0.79 KDM4E (0.31) ALDH1A1TP53HPGDPTGS1HBB
2,6-Diaminopurine SCHEMBL29444619 0.79 GDA (0.48) GDAPDPK1XDHUSP2ALDH1A1
2,6-Diaminopurine SCHEMBL6423146 0.78 GDA (0.47) GDAPDPK1XDHUSP2ALDH1A1
2,6-Diaminopurine SCHEMBL8757968 0.78 GDA (0.47) GDAPDPK1XDHUSP2ALDH1A1
SCHEMBL5582500 0.76 GDA (0.33) GDAPDPK1XDHUSP2ALDH1A1
SCHEMBL842437 0.76 CSNK2A1 (0.36) GDAPDPK1XDHUSP2ALDH1A1
SCHEMBL6545701 0.76 GDA (0.34) GDAPDPK1XDHUSP2ALDH1A1
SCHEMBL22700248 0.76 GDA (0.33) GDAPDPK1XDHUSP2ALDH1A1
SCHEMBL11977311 0.76 GDA (0.33) GDAPDPK1XDHUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250172493-A1 OPTICAL FOREIGN SUBSTANCE DETECTION DEVICE USING LIGHT SCATTERING AND IMAGE ANALYSIS JEDEX INC. (KR) 2025-05-29 US claimed
CN-119563102-A Optical foreign matter detection device using light scattering and image analysis 杰德克思股份有限公司 2025-03-04 CN claimed
WO-2024039005-A1 OPTICAL FOREIGN MATTER DETECTION DEVICE USING LIGHT SCATTERING AND IMAGE ANALYSIS 주식회사 제덱스 2024-02-22 WO claimed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 US claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US claimed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
EP-3157572-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. 2016-10-20 US claimed
EP-3080289-A2 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2016-10-19 EP claimed
WO-2015196130-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 WO claimed
CN-104447746-A Compound for activating AMPK and application thereof HUAAN MEDICAL CO LTD 2015-03-25 CN claimed
US-20140303112-A1 Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) ENERGENESIS BIOMEDICAL CO., LTD (TW) 2014-10-09 US claimed
WO-2014093924-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2014-06-19 WO claimed
US-20030082101-A1 Accelerators for increasing the rate of formation of free radicals and reactive oxygen species CAVALIER DISCOVERY 2003-05-01 US claimed
WO-2002100478-A9 ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES CAVALIER DISCOVERY (US) 2003-03-27 WO claimed
WO-2002100478-A2 ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES CAVALIER DISCOVERY (US) 2002-12-19 WO claimed
JP-2002509155-A 2002-03-26 JP claimed
EP-1047705-A2 NUCLEOBASE OLIGOMERS THE PERKIN-ELMER CORPORATION (US) 2000-11-02 EP claimed
US-6054568-A Nucleobase oligomers THE PERKIN-ELMER CORPORATION (US) 2000-04-25 US claimed
WO-1999036429-A2 NUCLEOBASE OLIGOMERS THE PERKIN-ELMER CORPORATION (US) 1999-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082101-A1 Accelerators for increasing the rate of formation of free radicals and reactive oxygen species SOD1, SOD3, APEX1 GDA 439/4885PDPK1 3581/4885XDH 499/4885
US-20140303112-A1 Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) PRKAG2, PRKAB2, PRKAG1 GDA 1170/4885PDPK1 281/4885XDH 253/4885
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 GDA 36/4885PDPK1 3533/4885XDH 2049/4885
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 GDA 83/4885PDPK1 3868/4885XDH 1523/4885
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 GDA 83/4885PDPK1 3868/4885XDH 1523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.