Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478800 | 0.75 | AGTR1 (0.38) | LMNAPOLBAGTR1AGTR2MAPT | |
| SCHEMBL9478463 | 0.74 | MAPT (0.41) | LMNAHSD17B10HPGDPOLBMAPT | |
| SCHEMBL8095006 | 0.72 | HSD17B10 (0.48) | ALDH1A1TSHRHSD17B10CLK4MEN1 | |
| SCHEMBL8953484 | 0.71 | MYC (0.38) | ALDH1A1TSHRHSD17B10CLK4MEN1 | |
| SCHEMBL9340760 | 0.67 | ACHE (0.49) | AGTR1 | |
| SCHEMBL20183521 | 0.66 | HSD17B10 (0.53) | ALDH1A1TSHRHSD17B10CLK4MEN1 | |
| SCHEMBL9034499 | 0.64 | BDKRB1 (0.46) | ALDH1A1TSHRHSD17B10CLK4MEN1 | |
| SCHEMBL14329705 | 0.63 | EGLN1 (0.57) | ALDH1A1KDM4EPOLBCNR2 | |
| SCHEMBL9532902 | 0.63 | MYC (0.43) | ALDH1A1LMNATSHRHSD17B10CLK4 | |
| SCHEMBL31006531 | 0.63 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10CLK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242928-A | Angiotensin II antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-07 | — | — | US | disclosed |